blog: #!/perl/bioinfo
postal address
Laboratorio de Biología Computacional y Estructural, Estación Experimental Aula Dei-CSIC, Av. Montañana 1.005, 50059 Zaragoza (Spain)
phone (+34) 976716089
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rutas en bicicleta de Zaragoza al campus de Aula Dei |
- genomics and transcriptional regulation of grasses, in collaboration with Ana Casas, Ernesto Igartua, Pilar Catalán and the RSAT team
- evolutionary and structural analysis of transcription factors and disordered proteins in plants
- phylogenomic analyses and markers for breeding, molecular diagnostics and metagenomics, in collaboration with Pablo Vinuesa (UNAM,México)
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Maximum-likelihood pan-genome phylogeny estimated with IQ-TREE from the consensus pan-genome clusters of Stenotrophomonas displayed in the Venn diagram |
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a) Alignment of Vrs1.b2, vrs1.a2, and Vrs1.b5 DNA partial sequences of exon 2. b) Multiple alignment of protein sequences of different alleles of the Vrs1 gene. c) Barley spikes from Spanish landraces SBCC039 (vrs1.a2) six-rowed (left) and SBCC155 (Vrs1.b5) two-rowed (right) |
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Gene-based pan-genome of Brachypodium distachyon. B,C) Core, softcore, shell, cloud genes. D) % coverage of 37,886 high-confidence pan-genes by short read data sets from 49 lines. |
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Nuclear and plastid filogenomic trees of Brachypodium distachyon ecotypes. |
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Pan-genome of CDS annotated in 19 Arabidopsis thaliana ecotypes. A) Occupancy of CDS clusters. B) Pan-genome growth simulations. C) Mean expression of CDS in root, seedling and floral buds. D) dN/dS ratio of single-copy CDS clusters. |
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Schematic representation of the 4 stages of the MEBS algorithm focusing on the Sulphur-cycle. |
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Total disordered residues in transcription factors (PONDR VLS2b) vs number of tissues in several plant species. |
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Design of stress treatments and leaf water potential of barley SBCC073 (73) and Scarlett (SC) plants. |
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Heterozygous mappings in barley occur when relevant loci are absent from the reference genome assembly. |
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Model of nucleosome sandwich incorporating a single H2BGFP molecule (in red). The steric difficulty to accommodate the GFP tag increases if we consider that each nucleosome may contain up to two molecules of GFP. |
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Annotation of interface residues in footprintDB. |
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(A) Sequence logos of the R2 and R3 recognition α-helices of Arabidopsis thaliana R2R3-MYB DBD subgroups (left) and of the bound cis-elements assayed on the Y1H experiments, classified into two groups (right). |
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BARLEYMAP pipeline |
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Distribution of predicted disordered segments with length>30 in plants. Disorder in chloroplast (Cp), mitochondria (Mt) and nuclear (Nu) proteomes are shown. |
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footprint of dimeric complex 2bam_AB |
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A few active transcriptional subnetworks in Escherichia coli (details here) |
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ML tree of plant-like FADS proteins (details here) |
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Multiple interface alignment of zinc fingers (details here) |
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DNAPROT algorithm (details here) |
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structure-based position weight matrix for Escherichia coli FNR, modelled with TFmodeller |
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comparative model of a protein-DNA complex |
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conceptual model of evolutionary role of binding specificity in bacterial regulatory networks |
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genomic benchmark of primers4clades |
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congruence of tree topologies derived from single and concatenated loci of Bradyrhizobium |
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benchmark of fragment-based comparative modelling approaches |